Product fact sheet
Lotrimin Ultra Butenafine Hydrochloride Cream 1%
Lotrimin Ultra contains butenafine hydrochloride 1% cream with a label specific to interdigital athlete's foot and explicit nail, scalp and mucosal exclusions.
A butenafine hydrochloride 1% cream whose current label is specific about athlete's foot between the toes and states that effectiveness on the bottom or sides of the foot is unknown.
interdigital athlete's-foot comparisons, comparing butenafine 1% against terbinafine, clotrimazole or tolnaftate
nail fungus, scalp infection, vaginal yeast infection, assuming evidence for the bottom/sides of the foot from an interdigital label
Key tradeoff: The label supports a relatively short interdigital athlete's-foot regimen but is unusually explicit about uncertainty for other foot locations.
This is a factual fit-and-tradeoff summary, not a product recommendation. Formula, device and brand claims remain manufacturer claims unless the cited source is explicitly regulatory or independent testing.
Why the location wording matters
Lotrimin Ultra contains butenafine hydrochloride 1%. The current Drug Facts label says it cures most athlete’s foot between the toes and explicitly states that effectiveness on the bottom or sides of the foot is unknown.
For ages 12 and older, the label lists either twice-daily application for 1 week or once-daily application for 4 weeks for interdigital athlete’s foot.
What not to infer
The label says not to use this cream on nails or scalp, near the mouth or eyes, or for vaginal yeast infections. The brand name should not override those formulation-specific boundaries.
Location-specific comparison
Effectiveness on the bottom or sides of the foot is listed as unknown on the cited label, so that boundary should remain visible when comparing athlete’s-foot products. Compare the location-specific label with Lamisil AT terbinafine 1%, which separately labels between-toe and bottom/side athlete’s foot regimens, plus Lotrimin clotrimazole 1% and Tinactin tolnaftate 1%.
Formula facts
Ingredients, actives and label details
- Product form
- Cream Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Active ingredient
- Butenafine hydrochloride Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Active concentration
- 1% Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Labeled use
- Most athlete's foot between the toes; label states effectiveness on bottom or sides of foot is unknown Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Key directions
- Age 12+: between toes twice daily for 1 week or once daily for 4 weeks Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Age label
- 12 years and older; under 12 ask a doctor Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Important scope warning
- Do not use on nails or scalp, in/near mouth or eyes, or for vaginal yeast infections Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
- Full inactive ingredient list
- Available in current DailyMed label Basis: Government drug label Source: LOTRIMIN ULTRA - butenafine hydrochloride cream
Source labels preserve provenance. Manufacturer specifications, ingredient lists and performance claims are not treated as independent clinical evidence; regulatory records and independent measurements are identified separately when available.
Safety first
What should make you slow down?
The current label is specific to external skin use and explicitly excludes nails, scalp, mouth/eye areas and vaginal yeast infections.
- For athlete's foot, the cited label specifically addresses infection between the toes and says effectiveness on the bottom or sides of the foot is unknown.
- Children under 12 should ask a doctor before use.
- Do not extrapolate this cream to nail fungus or vaginal candidiasis.
Where to buy
Current tracked merchants
Commerce note: merchant economics never enter our editorial score. Affiliate links are identified as (paid link) and use sponsored-link markup.
No merchant destination is currently tracked for this product.
Source trail
Primary documents and supporting evidence
- LOTRIMIN ULTRA - butenafine hydrochloride creamDailyMed, U.S. National Library of Medicine · Regulatory · retrieved 2026-08-11
- Treatment of RingwormCenters for Disease Control and Prevention · Government health · retrieved 2026-08-11